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COVID-19 Vaccine Acceptance Level in Ethiopia: A Systematic Review and Meta-Analysis

BACKGROUND: The coronavirus disease 2019 pandemic has had a devastating impact on the everyday lives of the world's population and to this end, the development of curative vaccines was upheld as a welcome panacea. Despite the undeniable negative impact of the disease on human beings, lower than...

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Autores principales: Sahile, Addisu Tadesse, Gizaw, Girma Demissie, Mgutshini, Tennyson, Gebremariam, Zewdu Minwuyelet, Bekele, Getabalew Endazenaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436617/
https://www.ncbi.nlm.nih.gov/pubmed/36061634
http://dx.doi.org/10.1155/2022/2313367
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author Sahile, Addisu Tadesse
Gizaw, Girma Demissie
Mgutshini, Tennyson
Gebremariam, Zewdu Minwuyelet
Bekele, Getabalew Endazenaw
author_facet Sahile, Addisu Tadesse
Gizaw, Girma Demissie
Mgutshini, Tennyson
Gebremariam, Zewdu Minwuyelet
Bekele, Getabalew Endazenaw
author_sort Sahile, Addisu Tadesse
collection PubMed
description BACKGROUND: The coronavirus disease 2019 pandemic has had a devastating impact on the everyday lives of the world's population and to this end, the development of curative vaccines was upheld as a welcome panacea. Despite the undeniable negative impact of the disease on human beings, lower than expected proportions of people have taken up the vaccines, particularly in the developing non-Western world. Ethiopia represents an interesting case example, of a nation where COVID-19 vaccine acceptance levels have not been well investigated and a need exists to assess the overall level of vaccine acceptance. METHODS: A systematic multidatabase search for relevant articles was carried out across Google Scholar, Web of Science, Science Direct, Hinari, EMBASE, Boolean operator, and PubMed. Two reviewers independently selected, reviewed, screened, and extracted data by using a Microsoft Excel spreadsheet. The Joanna Briggs Institute prevalence critical appraisal tools and the modified NewcastleOttawa Scale (NOS) were used to assess the quality of evidence. All studies conducted in Ethiopia, reporting vaccine acceptance rates were incorporated. The extracted data were imported into the comprehensive meta-analysis version 3.0 for further analysis. Heterogeneity was confirmed using Higgins's method, and publication bias was checked by using Beggs and Eggers tests. A random-effects meta-analysis model with a 95% confidence interval was computed to estimate the pooled prevalence. Furthermore, subgroup analysis based on the study area and sample size was done. Results and Conclusion. After reviewing 67 sources, 18 articles fulfilled the inclusion criteria and were included in the meta-analysis. The pooled prevalence of COVID-19 vaccine acceptance in Ethiopia was 57.8% (95% CI: 47.2%–67.8%). The level of COVID-19 vaccine acceptance in Ethiopia was at a lower rate than necessary to achieve herd immunity. The highest level of vaccine acceptance rate was reported via online or telephone surveys followed by the southern region of Ethiopia. The lowest vaccine acceptance patterns were reported in Addis Ababa.
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spelling pubmed-94366172022-09-02 COVID-19 Vaccine Acceptance Level in Ethiopia: A Systematic Review and Meta-Analysis Sahile, Addisu Tadesse Gizaw, Girma Demissie Mgutshini, Tennyson Gebremariam, Zewdu Minwuyelet Bekele, Getabalew Endazenaw Can J Infect Dis Med Microbiol Review Article BACKGROUND: The coronavirus disease 2019 pandemic has had a devastating impact on the everyday lives of the world's population and to this end, the development of curative vaccines was upheld as a welcome panacea. Despite the undeniable negative impact of the disease on human beings, lower than expected proportions of people have taken up the vaccines, particularly in the developing non-Western world. Ethiopia represents an interesting case example, of a nation where COVID-19 vaccine acceptance levels have not been well investigated and a need exists to assess the overall level of vaccine acceptance. METHODS: A systematic multidatabase search for relevant articles was carried out across Google Scholar, Web of Science, Science Direct, Hinari, EMBASE, Boolean operator, and PubMed. Two reviewers independently selected, reviewed, screened, and extracted data by using a Microsoft Excel spreadsheet. The Joanna Briggs Institute prevalence critical appraisal tools and the modified NewcastleOttawa Scale (NOS) were used to assess the quality of evidence. All studies conducted in Ethiopia, reporting vaccine acceptance rates were incorporated. The extracted data were imported into the comprehensive meta-analysis version 3.0 for further analysis. Heterogeneity was confirmed using Higgins's method, and publication bias was checked by using Beggs and Eggers tests. A random-effects meta-analysis model with a 95% confidence interval was computed to estimate the pooled prevalence. Furthermore, subgroup analysis based on the study area and sample size was done. Results and Conclusion. After reviewing 67 sources, 18 articles fulfilled the inclusion criteria and were included in the meta-analysis. The pooled prevalence of COVID-19 vaccine acceptance in Ethiopia was 57.8% (95% CI: 47.2%–67.8%). The level of COVID-19 vaccine acceptance in Ethiopia was at a lower rate than necessary to achieve herd immunity. The highest level of vaccine acceptance rate was reported via online or telephone surveys followed by the southern region of Ethiopia. The lowest vaccine acceptance patterns were reported in Addis Ababa. Hindawi 2022-08-25 /pmc/articles/PMC9436617/ /pubmed/36061634 http://dx.doi.org/10.1155/2022/2313367 Text en Copyright © 2022 Addisu Tadesse Sahile et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sahile, Addisu Tadesse
Gizaw, Girma Demissie
Mgutshini, Tennyson
Gebremariam, Zewdu Minwuyelet
Bekele, Getabalew Endazenaw
COVID-19 Vaccine Acceptance Level in Ethiopia: A Systematic Review and Meta-Analysis
title COVID-19 Vaccine Acceptance Level in Ethiopia: A Systematic Review and Meta-Analysis
title_full COVID-19 Vaccine Acceptance Level in Ethiopia: A Systematic Review and Meta-Analysis
title_fullStr COVID-19 Vaccine Acceptance Level in Ethiopia: A Systematic Review and Meta-Analysis
title_full_unstemmed COVID-19 Vaccine Acceptance Level in Ethiopia: A Systematic Review and Meta-Analysis
title_short COVID-19 Vaccine Acceptance Level in Ethiopia: A Systematic Review and Meta-Analysis
title_sort covid-19 vaccine acceptance level in ethiopia: a systematic review and meta-analysis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436617/
https://www.ncbi.nlm.nih.gov/pubmed/36061634
http://dx.doi.org/10.1155/2022/2313367
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