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Recurrence of renal cell carcinoma after simultaneous radical nephrectomy and cadaver renal transplant

INTRODUCTION: Generally, renal transplantation is contraindicated in cancer patients, and a certain follow‐up period is required. We report a case of late recurrence of renal cell carcinoma in a patient who underwent simultaneous radical nephrectomy and cadaver renal transplantation due to renal cel...

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Autores principales: Inoue, Shinya, Shioya, Akihiro, Kunii, Kenshirou, Suga, Kodai, Morita, Nobuyo, Chikazawa, Ippei, Tanaka, Tatsuro, Miyazawa, Katsuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436674/
https://www.ncbi.nlm.nih.gov/pubmed/36090937
http://dx.doi.org/10.1002/iju5.12499
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author Inoue, Shinya
Shioya, Akihiro
Kunii, Kenshirou
Suga, Kodai
Morita, Nobuyo
Chikazawa, Ippei
Tanaka, Tatsuro
Miyazawa, Katsuhito
author_facet Inoue, Shinya
Shioya, Akihiro
Kunii, Kenshirou
Suga, Kodai
Morita, Nobuyo
Chikazawa, Ippei
Tanaka, Tatsuro
Miyazawa, Katsuhito
author_sort Inoue, Shinya
collection PubMed
description INTRODUCTION: Generally, renal transplantation is contraindicated in cancer patients, and a certain follow‐up period is required. We report a case of late recurrence of renal cell carcinoma in a patient who underwent simultaneous radical nephrectomy and cadaver renal transplantation due to renal cell carcinoma observed during renal transplantation after 12 years. CASE PRESENTATION: Incidental renal cell carcinoma was found in a 48‐year‐old man during kidney transplantation who subsequently underwent simultaneous cadaver kidney transplantation and radical nephrectomy. Twelve years after transplantation, he developed an anterior mediastinal tumor, a lung tumor which was resected and a right adrenal gland mass which was resected along with the right kidney. Currently, he is being treated with tyrosine kinase inhibitors owing to the metastasis in the left adrenal gland. CONCLUSION: In patients with metastatic carcinoma undergoing renal transplant, the indications for surgical procedures and choice of immunosuppressants should be carefully considered.
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spelling pubmed-94366742022-09-09 Recurrence of renal cell carcinoma after simultaneous radical nephrectomy and cadaver renal transplant Inoue, Shinya Shioya, Akihiro Kunii, Kenshirou Suga, Kodai Morita, Nobuyo Chikazawa, Ippei Tanaka, Tatsuro Miyazawa, Katsuhito IJU Case Rep Case Reports INTRODUCTION: Generally, renal transplantation is contraindicated in cancer patients, and a certain follow‐up period is required. We report a case of late recurrence of renal cell carcinoma in a patient who underwent simultaneous radical nephrectomy and cadaver renal transplantation due to renal cell carcinoma observed during renal transplantation after 12 years. CASE PRESENTATION: Incidental renal cell carcinoma was found in a 48‐year‐old man during kidney transplantation who subsequently underwent simultaneous cadaver kidney transplantation and radical nephrectomy. Twelve years after transplantation, he developed an anterior mediastinal tumor, a lung tumor which was resected and a right adrenal gland mass which was resected along with the right kidney. Currently, he is being treated with tyrosine kinase inhibitors owing to the metastasis in the left adrenal gland. CONCLUSION: In patients with metastatic carcinoma undergoing renal transplant, the indications for surgical procedures and choice of immunosuppressants should be carefully considered. John Wiley and Sons Inc. 2022-06-24 /pmc/articles/PMC9436674/ /pubmed/36090937 http://dx.doi.org/10.1002/iju5.12499 Text en © 2022 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Urological Association. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Inoue, Shinya
Shioya, Akihiro
Kunii, Kenshirou
Suga, Kodai
Morita, Nobuyo
Chikazawa, Ippei
Tanaka, Tatsuro
Miyazawa, Katsuhito
Recurrence of renal cell carcinoma after simultaneous radical nephrectomy and cadaver renal transplant
title Recurrence of renal cell carcinoma after simultaneous radical nephrectomy and cadaver renal transplant
title_full Recurrence of renal cell carcinoma after simultaneous radical nephrectomy and cadaver renal transplant
title_fullStr Recurrence of renal cell carcinoma after simultaneous radical nephrectomy and cadaver renal transplant
title_full_unstemmed Recurrence of renal cell carcinoma after simultaneous radical nephrectomy and cadaver renal transplant
title_short Recurrence of renal cell carcinoma after simultaneous radical nephrectomy and cadaver renal transplant
title_sort recurrence of renal cell carcinoma after simultaneous radical nephrectomy and cadaver renal transplant
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436674/
https://www.ncbi.nlm.nih.gov/pubmed/36090937
http://dx.doi.org/10.1002/iju5.12499
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