Primary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: A case report and literature review

Here, we report a case of metastatic Epstein–Barr virus (EBV)‐related primary pulmonary lymphoepithelioma‐like carcinoma (PPLELC) in a young, nonsmoking female who responded well to treatment with two types of immune checkpoint inhibitors (ICIs). This is the first case report of a favorable outcome...

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Autores principales: Archwamety, Anita, Ruangchira‐urai, Ruchira, Akewanlop, Charuwan, Korphaisarn, Krittiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436678/
https://www.ncbi.nlm.nih.gov/pubmed/35830974
http://dx.doi.org/10.1111/1759-7714.14580
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author Archwamety, Anita
Ruangchira‐urai, Ruchira
Akewanlop, Charuwan
Korphaisarn, Krittiya
author_facet Archwamety, Anita
Ruangchira‐urai, Ruchira
Akewanlop, Charuwan
Korphaisarn, Krittiya
author_sort Archwamety, Anita
collection PubMed
description Here, we report a case of metastatic Epstein–Barr virus (EBV)‐related primary pulmonary lymphoepithelioma‐like carcinoma (PPLELC) in a young, nonsmoking female who responded well to treatment with two types of immune checkpoint inhibitors (ICIs). This is the first case report of a favorable outcome to ICIs in the late‐line treatment of advanced PPLELC patients with programmed cell death‐ligand 1 (PD‐L1) expression.
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spelling pubmed-94366782022-09-09 Primary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: A case report and literature review Archwamety, Anita Ruangchira‐urai, Ruchira Akewanlop, Charuwan Korphaisarn, Krittiya Thorac Cancer Case Reports Here, we report a case of metastatic Epstein–Barr virus (EBV)‐related primary pulmonary lymphoepithelioma‐like carcinoma (PPLELC) in a young, nonsmoking female who responded well to treatment with two types of immune checkpoint inhibitors (ICIs). This is the first case report of a favorable outcome to ICIs in the late‐line treatment of advanced PPLELC patients with programmed cell death‐ligand 1 (PD‐L1) expression. John Wiley & Sons Australia, Ltd 2022-07-13 2022-09 /pmc/articles/PMC9436678/ /pubmed/35830974 http://dx.doi.org/10.1111/1759-7714.14580 Text en © 2022 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Archwamety, Anita
Ruangchira‐urai, Ruchira
Akewanlop, Charuwan
Korphaisarn, Krittiya
Primary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: A case report and literature review
title Primary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: A case report and literature review
title_full Primary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: A case report and literature review
title_fullStr Primary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: A case report and literature review
title_full_unstemmed Primary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: A case report and literature review
title_short Primary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: A case report and literature review
title_sort primary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: a case report and literature review
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436678/
https://www.ncbi.nlm.nih.gov/pubmed/35830974
http://dx.doi.org/10.1111/1759-7714.14580
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