Cargando…

Distinctive populations of CD4(+)T cells associated with vaccine efficacy

Memory T cells underpin vaccine-induced immunity but are not yet fully understood. To distinguish features of memory cells that confer protective immunity, we used single cell transcriptome analysis to compare antigen-specific CD4(+)T cells recalled to lungs of mice that received a protective or non...

Descripción completa

Detalles Bibliográficos
Autores principales:	Woodring, Therese, Dewey, Colin N., Santos Dias, Lucas Dos, He, Xin, Dobson, Hannah E., Wüthrich, Marcel, Klein, Bruce
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436750/ https://www.ncbi.nlm.nih.gov/pubmed/36060075 http://dx.doi.org/10.1016/j.isci.2022.104934

Ejemplares similares

Combination Adjuvants Enhance Recombinant Protein Vaccine Protection against Fungal Infection
por: Wüthrich, Marcel, et al.
Publicado: (2021)

Vaccine Immunity to Pathogenic Fungi Overcomes the Requirement for CD4 Help in Exogenous Antigen Presentation to CD8(+) T Cells: Implications for Vaccine Development in Immune-deficient Hosts
por: Wüthrich, Marcel, et al.
Publicado: (2003)

Variation in Host Resistance to Blastomyces dermatitidis: Potential Use of Genetic Reference Panels and Advances in Immunophenotyping of Diverse Mouse Strains
por: Kohn, Elaine M., et al.
Publicado: (2022)

Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance
por: Dobson, Hannah E., et al.
Publicado: (2020)

Tc17 Cells Mediate Vaccine Immunity against Lethal Fungal Pneumonia in Immune Deficient Hosts Lacking CD4(+) T Cells
por: Nanjappa, Som Gowda, et al.
Publicado: (2012)

Virally-vectored vaccine candidates against white-nose syndrome induce anti-fungal immune response in little brown bats (Myotis lucifugus)
por: Rocke, Tonie E., et al.
Publicado: (2019)

Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia
por: Nanjappa, Som Gowda, et al.
Publicado: (2015)

Targeted Gene Disruption Reveals an Adhesin Indispensable for Pathogenicity of Blastomyces dermatitidis
por: Tristan Brandhorst, T., et al.
Publicado: (1999)

Neutrophil Cells Are Essential for The Efficacy of a Therapeutic Vaccine against Paracoccidioidomycosis
por: Dias, Lucas dos Santos, et al.
Publicado: (2021)

MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4(+) T Cells during the Contraction Phase
por: Wang, Huafeng, et al.
Publicado: (2016)

Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity
por: dos Santos Dias, Lucas, et al.
Publicado: (2021)

Ligation of Dectin-2 with a novel microbial ligand promotes adjuvant activity for vaccination
por: Wang, Huafeng, et al.
Publicado: (2017)

Antifungal Tc17 cells are durable and stable, persisting as long-lasting vaccine memory without plasticity towards IFNγ cells
por: Nanjappa, Som Gowda, et al.
Publicado: (2017)

Novel Strategies to Enhance Vaccine Immunity against Coccidioidomycosis
por: Cole, Garry T., et al.
Publicado: (2013)

Pseudomonas poae–Associated Fatal Septic Transfusion Reaction, Peoria, Illinois, USA, 2017
por: Woodring, Therese S., et al.
Publicado: (2019)

The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure
por: Garfoot, Andrew L., et al.
Publicado: (2016)

Characterization of C-type lectins reveals an unexpectedly limited interaction between Cryptococcus neoformans spores and Dectin-1
por: Walsh, Naomi M., et al.
Publicado: (2017)

Identification of human CD4(+) T cell populations with distinct antitumor activity
por: Nelson, Michelle H., et al.
Publicado: (2020)

Iterative sorting reveals CD133+ and CD133- melanoma cells as phenotypically distinct populations
por: Grasso, Carole, et al.
Publicado: (2016)

Fonsecaea pedrosoi‐induced Th17‐cell differentiation in mice is fostered by Dectin‐2 and suppressed by Mincle recognition
por: Wüthrich, Marcel, et al.
Publicado: (2015)

Regulation of B cell responses by distinct populations of CD4 T cells
por: Aloulou, Meryem, et al.
Publicado: (2019)

CD28 and CD57 define four populations with distinct phenotypic properties within human CD8(+) T cells
por: Pangrazzi, Luca, et al.
Publicado: (2019)

A distinct CD38(+)CD45RA(+) population of CD4(+), CD8(+), and double-negative T cells is controlled by FAS
por: Maccari, Maria Elena, et al.
Publicado: (2020)

Early immune response against Fonsecaea pedrosoi requires Dectin-2-mediated Th17 activity, whereas Th1 response, aided by Treg cells, is crucial for fungal clearance in later stage of experimental chromoblastomycosis
por: Siqueira, Isaque Medeiros, et al.
Publicado: (2020)

Vaccine efficacy against SARS-CoV-2 for Pfizer BioNTech, Moderna, and AstraZeneca vaccines: a systematic review
por: Reynolds, Lia, et al.
Publicado: (2023)

Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection
por: Auclair, Sarah, et al.
Publicado: (2018)

Transcription Factor KLF2 in Dendritic Cells Downregulates Th2 Programming via the HIF-1α/Jagged2/Notch Axis
por: Xiong, Ye, et al.
Publicado: (2016)

O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures
por: Garfoot, Andrew L., et al.
Publicado: (2018)

Complement Component 3C3 and C3a Receptor Are Required in Chitin-Dependent Allergic Sensitization to Aspergillus fumigatus but Dispensable in Chitin-Induced Innate Allergic Inflammation
por: Roy, René M., et al.
Publicado: (2013)

CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen Blastomyces dermatitidis
por: Kujoth, Gregory C., et al.
Publicado: (2018)

Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages
por: Murgaski, Aleksandar, et al.
Publicado: (2022)

CD4(+) T cell activation promotes the differential release of distinct populations of nanosized vesicles
por: van der Vlist, Els J., et al.
Publicado: (2012)

RSV Vaccine-Enhanced Disease Is Orchestrated by the Combined Actions of Distinct CD4 T Cell Subsets
por: Knudson, Cory J., et al.
Publicado: (2015)

Distinctive CD26 Expression on CD4 T-Cell Subsets
por: Cordero, Oscar J., et al.
Publicado: (2021)

Infectious particle identity determines dissemination and disease outcome for the inhaled human fungal pathogen Cryptococcus
por: Walsh, Naomi M., et al.
Publicado: (2019)

CD63, MHC class 1, and CD47 identify subsets of extracellular vesicles containing distinct populations of noncoding RNAs
por: Kaur, Sukhbir, et al.
Publicado: (2018)

Distinct populations of antigen-specific tissue-resident CD8(+) T cells in human cervix mucosa
por: Peng, Tao, et al.
Publicado: (2021)

In vivo antigen expression regulates CD4 T cell differentiation and vaccine efficacy against Mycobacterium tuberculosis infection
por: Clemmensen, Helena Strand, et al.
Publicado: (2021)

In Vivo Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection
por: Clemmensen, Helena Strand, et al.
Publicado: (2021)

CD20 positive CD8 T cells are a unique and transcriptionally-distinct subset of T cells with distinct transmigration properties
por: Vlaming, Martijn, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oid2e3a3bt8rk011qfr76n8q7q