Pre-existing partner-drug resistance to artemisinin combination therapies facilitates the emergence and spread of artemisinin resistance: a consensus modelling study

BACKGROUND: Artemisinin-resistant genotypes of Plasmodium falciparum have now emerged a minimum of six times on three continents despite recommendations that all artemisinins be deployed as artemisinin combination therapies (ACTs). Widespread resistance to the non-artemisinin partner drugs in ACTs h...

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Detalles Bibliográficos
Autores principales: Watson, Oliver J, Gao, Bo, Nguyen, Tran Dang, Tran, Thu Nguyen-Anh, Penny, Melissa A, Smith, David L, Okell, Lucy, Aguas, Ricardo, Boni, Maciej F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436785/
https://www.ncbi.nlm.nih.gov/pubmed/35931099
http://dx.doi.org/10.1016/S2666-5247(22)00155-0

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