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Lysyl oxidase-like 1 deficiency alters ultrastructural and biomechanical properties of the peripapillary sclera in mice

Lysyl oxidase-like 1 encoded by the LOXL1 gene is a member of the lysyl oxidase family of enzymes that are important in the maintenance of extracellular matrix (ECM)-rich tissue. LOXL1 is important for proper elastic fiber formation and mice lacking LOXL1 (Loxl1(−/−)) exhibit systemic elastic fiber...

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Detalles Bibliográficos
Autores principales:	Wareham, Lauren K., Kuchtey, John, Wu, Hang-Jing, Krystofiak, Evan, Wu, Yusheng, Reinhart-King, Cynthia A., Kuchtey, Rachel W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436796/ https://www.ncbi.nlm.nih.gov/pubmed/36060791 http://dx.doi.org/10.1016/j.mbplus.2022.100120

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