O-GlcNAcylation stabilizes the autophagy-initiating kinase ULK1 by inhibiting chaperone-mediated autophagy upon HPV infection

Human papillomaviruses (HPVs) cause a subset of head and neck squamous cell carcinomas (HNSCCs). Previously, we demonstrated that HPV16 oncogene E6 or E6/E7 transduction increases the abundance of O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT), but OGT substrates affected by this increa...

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Detalles Bibliográficos
Autores principales: Shi, Yingxin, Yan, Sheng, Shao, Guang-Can, Wang, Jinglong, Jian, Yong-Ping, Liu, Bo, Yuan, Yanqiu, Qin, Ke, Nai, Shanshan, Huang, Xiahe, Wang, Yingchun, Chen, Zhenghui, Chen, Xing, Dong, Meng-Qiu, Geng, Yiqun, Xu, Zhi-Xiang, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436821/
https://www.ncbi.nlm.nih.gov/pubmed/35931119
http://dx.doi.org/10.1016/j.jbc.2022.102341

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