Transcriptional coregulator Ess2 controls survival of post-thymic CD4(+) T cells through the Myc and IL-7 signaling pathways

Ess2, also known as Dgcr14, is a transcriptional co-regulator of CD4(+) T cells. Ess2 is located in a chromosomal region, the loss of which has been associated with 22q11.2 deletion syndrome (22q11DS), which causes heart defects, skeletal abnormalities, and immunodeficiency. However, the specific as...

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Detalles Bibliográficos
Autores principales: Takada, Ichiro, Hidano, Shinya, Takahashi, Sayuri, Yanaka, Kaori, Ogawa, Hidesato, Tsuchiya, Megumi, Yokoyama, Atsushi, Sato, Shingo, Ochi, Hiroki, Nakagawa, Tohru, Kobayashi, Takashi, Nakagawa, Shinichi, Makishima, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436822/
https://www.ncbi.nlm.nih.gov/pubmed/35933014
http://dx.doi.org/10.1016/j.jbc.2022.102342

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