Spatial quantitation of antibiotics in bone tissue compartments by laser-capture microdissection coupled with UHPLC-tandem mass spectrometry

Bones are the site of multiple diseases requiring chemotherapy, including cancer, arthritis, osteoporosis and infections. Yet limited methodologies are available to investigate the spatial distribution and quantitation of small molecule drugs in bone compartments, due to the difficulty of sectioning...

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Detalles Bibliográficos
Autores principales: Kaya, Firat, Zimmerman, Matthew D., Antilus-Sainte, Rosleine, Gengenbacher, Martin, Carter, Claire L., Dartois, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436889/
https://www.ncbi.nlm.nih.gov/pubmed/35945288
http://dx.doi.org/10.1007/s00216-022-04257-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436889/
https://www.ncbi.nlm.nih.gov/pubmed/35945288
http://dx.doi.org/10.1007/s00216-022-04257-3

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