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Ascorbate content of clinical glioma tissues is related to tumour grade and to global levels of 5-hydroxymethyl cytosine

Gliomas are incurable brain cancers with poor prognosis, with epigenetic dysregulation being a distinctive feature. 5-hydroxymethylcytosine (5-hmC), an intermediate generated in the demethylation of 5-methylcytosine, is present at reduced levels in glioma tissue compared with normal brain, and that...

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Detalles Bibliográficos
Autores principales:	Crake, Rebekah L. I., Burgess, Eleanor R., Wiggins, George A. R., Magon, Nicholas J., Das, Andrew B., Vissers, Margreet C. M., Morrin, Helen R., Royds, Janice A., Slatter, Tania L., Robinson, Bridget A., Phillips, Elisabeth, Dachs, Gabi U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436949/ https://www.ncbi.nlm.nih.gov/pubmed/36050369 http://dx.doi.org/10.1038/s41598-022-19032-8

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