Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism

Low body temperature predicts a poor outcome in patients with heart failure, but the underlying pathological mechanisms and implications are largely unknown. Brown adipose tissue (BAT) was initially characterised as a thermogenic organ, and recent studies have suggested it plays a crucial role in ma...

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Detalles Bibliográficos
Autores principales: Yoshida, Yohko, Shimizu, Ippei, Shimada, Atsuhiro, Nakahara, Keita, Yanagisawa, Sachiko, Kubo, Minoru, Fukuda, Shinji, Ishii, Chiharu, Yamamoto, Hiromitsu, Ishikawa, Takamasa, Kano, Kuniyuki, Aoki, Junken, Katsuumi, Goro, Suda, Masayoshi, Ozaki, Kazuyuki, Yoshida, Yutaka, Okuda, Shujiro, Ohta, Shigeo, Okamoto, Shiki, Minokoshi, Yasuhiko, Oda, Kanako, Sasaoka, Toshikuni, Abe, Manabu, Sakimura, Kenji, Kubota, Yoshiaki, Yoshimura, Norihiko, Kajimura, Shingo, Zuriaga, Maria, Walsh, Kenneth, Soga, Tomoyoshi, Minamino, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436957/
https://www.ncbi.nlm.nih.gov/pubmed/36050466
http://dx.doi.org/10.1038/s41598-022-19245-x

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