Docking study, molecular dynamic, synthesis, anti-α-glucosidase assessment, and ADMET prediction of new benzimidazole-Schiff base derivatives

The control of postprandial hyperglycemia is an important target in the treatment of type 2 diabetes mellitus (T2DM). As a result, targeting α-glucosidase as the most important enzyme in the breakdown of carbohydrates to glucose that leads to an increase in postprandial hyperglycemia is one of the t...

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Detalles Bibliográficos
Autores principales: Azizian, Homa, Pedrood, Keyvan, Moazzam, Ali, Valizadeh, Yousef, Khavaninzadeh, Kimia, Zamani, Ali, Mohammadi-Khanaposhtani, Maryam, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Hosseini, Samanesadat, Sarrafi, Yaghoub, Adibi, Hossein, Larijani, Bagher, Rastegar, Hossein, Mahdavi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437094/
https://www.ncbi.nlm.nih.gov/pubmed/36050498
http://dx.doi.org/10.1038/s41598-022-18896-0

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