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Glutamate drives ‘local Ca(2+) release’ in cardiac pacemaker cells

The sinoatrial node (SAN) is the origin of the electrical signals for rhythmic heartbeats in mammals. The spontaneous firing of SAN pacemaker cells (SANPCs) triggers cardiac contraction. ‘Local Ca(2+) release’ (LCR), a unique cellular activity, acts as the ‘engine’ of the spontaneous firing of SANPC...

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Detalles Bibliográficos
Autores principales: Xie, Duanyang, Xiong, Ke, Su, Xuling, Wang, Guanghua, Zou, Qicheng, Wang, Luxin, Zhang, Caihong, Cao, Yuting, Shao, Beihua, Zhang, Yixin, Zhang, Peidong, Liang, Dandan, Liu, Yi, Chen, Yi-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437105/
https://www.ncbi.nlm.nih.gov/pubmed/35840807
http://dx.doi.org/10.1038/s41422-022-00693-z