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Ruxolitinib inhibits cytokine production by human lung macrophages without impairing phagocytic ability
Background: The Janus kinase (JAK) 1/2 inhibitor ruxolitinib has been approved in an indication of myelofibrosis and is a candidate for the treatment of a number of inflammatory or autoimmune diseases. We assessed the effects of ruxolitinib on lipopolysaccharide (LPS)- and poly (I:C)-induced cytokin...
Autores principales: | Mantov, Nikola, Zrounba, Mathilde, Brollo, Marion, Grassin-Delyle, S, Glorion, Matthieu, David, Mélanie, Naline, Emmanuel, Devillier, Philippe, Salvator, Hélène |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437255/ https://www.ncbi.nlm.nih.gov/pubmed/36059986 http://dx.doi.org/10.3389/fphar.2022.896167 |
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