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Identification of a potent NAFLD drug candidate for controlling T2DM-mediated inflammation and secondary damage in vitro and in vivo

Accumulation of glucose/sugar results in the formation of reactive di-carbonyl compounds such as MGO and GO that interact with several amino acids and proteins to form toxic advanced glycation end products (AGEs). Induction of AGEs breakdown can control symptoms and severity in T2DM and other relate...

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Detalles Bibliográficos
Autores principales: Samsuzzaman, Md, Lee, Jae Hyuk, Moon, Hyejin, Lee, Jisue, Lee, Heaji, Lim, Yunsook, Park, Myoung Gyu, Kim, Hakwon, Kim, Sun Yeou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437277/
https://www.ncbi.nlm.nih.gov/pubmed/36059993
http://dx.doi.org/10.3389/fphar.2022.943879