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Computational modeling of protracted HCMV replication using genome substrates and protein temporal profiles

Human cytomegalovirus (HCMV) is a major cause of illness in immunocompromised individuals. The HCMV lytic cycle contributes to the clinical manifestations of infection. The lytic cycle occurs over ∼96 h in diverse cell types and consists of viral DNA (vDNA) genome replication and temporally distinct...

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Detalles Bibliográficos
Autores principales:	Monti, Christopher E., Mokry, Rebekah L., Schumacher, Megan L., Dash, Ranjan K., Terhune, Scott S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437303/ https://www.ncbi.nlm.nih.gov/pubmed/35994667 http://dx.doi.org/10.1073/pnas.2201787119

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