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Multiple Myeloma Uncovered Under Excessive Antacid and Chronic NSAID Use in a Young Female

Multiple myeloma (MM) is a plasma cell dyscrasia in which nearly all cases are diagnosed in patients over 40 years old. This report illustrates a case of a young female who presented with severe generalized weakness, acute kidney injury, hypercalcemia, and anemia. Her symptoms were initially attribu...

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Detalles Bibliográficos
Autores principales: Fujikawa, Priscilla, Brand, Kenneth, Shah, Siddharth, Munshi, Viraj, Patel, Kashyap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437417/
https://www.ncbi.nlm.nih.gov/pubmed/36072215
http://dx.doi.org/10.7759/cureus.27629
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author Fujikawa, Priscilla
Brand, Kenneth
Shah, Siddharth
Munshi, Viraj
Patel, Kashyap
author_facet Fujikawa, Priscilla
Brand, Kenneth
Shah, Siddharth
Munshi, Viraj
Patel, Kashyap
author_sort Fujikawa, Priscilla
collection PubMed
description Multiple myeloma (MM) is a plasma cell dyscrasia in which nearly all cases are diagnosed in patients over 40 years old. This report illustrates a case of a young female who presented with severe generalized weakness, acute kidney injury, hypercalcemia, and anemia. Her symptoms were initially attributed to chronic NSAID and antacid intake, especially given her young age. However, further workup was pursued to rule out other potential diagnoses despite her age. She was ultimately diagnosed with multiple myeloma and started on bortezomib, cyclophosphamide, and dexamethasone. This report emphasizes the importance of maintaining a broad differential diagnosis. Untrained physicians can easily overlook rare cases. Timely diagnosis and treatment are key, and therefore, a high degree of suspicion is crucial for this patient population.
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spelling pubmed-94374172022-09-06 Multiple Myeloma Uncovered Under Excessive Antacid and Chronic NSAID Use in a Young Female Fujikawa, Priscilla Brand, Kenneth Shah, Siddharth Munshi, Viraj Patel, Kashyap Cureus Internal Medicine Multiple myeloma (MM) is a plasma cell dyscrasia in which nearly all cases are diagnosed in patients over 40 years old. This report illustrates a case of a young female who presented with severe generalized weakness, acute kidney injury, hypercalcemia, and anemia. Her symptoms were initially attributed to chronic NSAID and antacid intake, especially given her young age. However, further workup was pursued to rule out other potential diagnoses despite her age. She was ultimately diagnosed with multiple myeloma and started on bortezomib, cyclophosphamide, and dexamethasone. This report emphasizes the importance of maintaining a broad differential diagnosis. Untrained physicians can easily overlook rare cases. Timely diagnosis and treatment are key, and therefore, a high degree of suspicion is crucial for this patient population. Cureus 2022-08-03 /pmc/articles/PMC9437417/ /pubmed/36072215 http://dx.doi.org/10.7759/cureus.27629 Text en Copyright © 2022, Fujikawa et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Fujikawa, Priscilla
Brand, Kenneth
Shah, Siddharth
Munshi, Viraj
Patel, Kashyap
Multiple Myeloma Uncovered Under Excessive Antacid and Chronic NSAID Use in a Young Female
title Multiple Myeloma Uncovered Under Excessive Antacid and Chronic NSAID Use in a Young Female
title_full Multiple Myeloma Uncovered Under Excessive Antacid and Chronic NSAID Use in a Young Female
title_fullStr Multiple Myeloma Uncovered Under Excessive Antacid and Chronic NSAID Use in a Young Female
title_full_unstemmed Multiple Myeloma Uncovered Under Excessive Antacid and Chronic NSAID Use in a Young Female
title_short Multiple Myeloma Uncovered Under Excessive Antacid and Chronic NSAID Use in a Young Female
title_sort multiple myeloma uncovered under excessive antacid and chronic nsaid use in a young female
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437417/
https://www.ncbi.nlm.nih.gov/pubmed/36072215
http://dx.doi.org/10.7759/cureus.27629
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