Centaur antibodies: Engineered chimeric equine-human recombinant antibodies

Hyper-immune antisera from large mammals, in particular horses, are routinely used for life-saving anti-intoxication intervention. While highly efficient, the use of these immunotherapeutics is complicated by possible recipient reactogenicity and limited availability. Accordingly, there is an urgent...

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Detalles Bibliográficos
Autores principales: Rosenfeld, Ronit, Alcalay, Ron, Zvi, Anat, Ben-David, Alon, Noy-Porat, Tal, Chitlaru, Theodor, Epstein, Eyal, Israeli, Ofir, Lazar, Shirley, Caspi, Noa, Barnea, Ada, Dor, Eyal, Chomsky, Inbar, Pitel, Shani, Makdasi, Efi, Zichel, Ran, Mazor, Ohad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437483/
https://www.ncbi.nlm.nih.gov/pubmed/36059507
http://dx.doi.org/10.3389/fimmu.2022.942317

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