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Dependence on the MUC1-C Oncoprotein in Classic, Variant, and Non–neuroendocrine Small Cell Lung Cancer
Small cell lung cancer (SCLC) is a recalcitrant malignancy defined by subtypes on the basis of differential expression of the ASCL1, NEUROD1, and POU2F3 transcription factors. The MUC1-C protein is activated in pulmonary epithelial cells by exposure to environmental carcinogens and promotes oncogene...
Autores principales: | Fushimi, Atsushi, Morimoto, Yoshihiro, Ishikawa, Satoshi, Yamashita, Nami, Bhattacharya, Atrayee, Daimon, Tatsuaki, Rajabi, Hasan, Jin, Caining, Hagiwara, Masayuki, Yasumizu, Yota, Luan, Zhou, Suo, Wenhao, Wong, Kwok-Kin, Withers, Henry, Liu, Song, Long, Mark D., Kufe, Donald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437561/ https://www.ncbi.nlm.nih.gov/pubmed/35612556 http://dx.doi.org/10.1158/1541-7786.MCR-22-0165 |
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