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Human Papillomavirus Integration Strictly Correlates with Global Genome Instability in Head and Neck Cancer

Human papillomavirus (HPV)-positive head and neck cancers, predominantly oropharyngeal squamous cell carcinoma (OPSCC), exhibit epidemiologic, clinical, and molecular characteristics distinct from those OPSCCs lacking HPV. We applied a combination of whole-genome sequencing and optical genome mappin...

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Detalles Bibliográficos
Autores principales: Labarge, Brandon, Hennessy, Max, Zhang, Lijun, Goldrich, David, Chartrand, Scott, Purnell, Carson, Wright, Sage, Goldenberg, David, Broach, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437566/
https://www.ncbi.nlm.nih.gov/pubmed/35657601
http://dx.doi.org/10.1158/1541-7786.MCR-21-0831

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