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Human Papillomavirus Integration Strictly Correlates with Global Genome Instability in Head and Neck Cancer
Human papillomavirus (HPV)-positive head and neck cancers, predominantly oropharyngeal squamous cell carcinoma (OPSCC), exhibit epidemiologic, clinical, and molecular characteristics distinct from those OPSCCs lacking HPV. We applied a combination of whole-genome sequencing and optical genome mappin...
Autores principales: | Labarge, Brandon, Hennessy, Max, Zhang, Lijun, Goldrich, David, Chartrand, Scott, Purnell, Carson, Wright, Sage, Goldenberg, David, Broach, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437566/ https://www.ncbi.nlm.nih.gov/pubmed/35657601 http://dx.doi.org/10.1158/1541-7786.MCR-21-0831 |
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