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Sickle cell cerebrovascular reactivity to a CO(2) stimulus: Too little, too slow

Background: Despite increased cerebral blood flow (CBF), cerebral infarcts occur in patients with sickle cell disease (SCD). This suggests increased CBF does not meet metabolic demand possibly due to compromised cerebral vasodilatory response. Hypothesis: In adult SCD patients, cerebrovascular react...

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Detalles Bibliográficos
Autores principales:	Forté, Stéphanie, Sobczyk, Olivia, Poublanc, Julien, Duffin, James, Hare, Gregory M. T., Fisher, Joseph Arnold, Mikulis, David, Kuo, Kevin H. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437621/ https://www.ncbi.nlm.nih.gov/pubmed/36060689 http://dx.doi.org/10.3389/fphys.2022.886807

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