Preclinical safety assessment of MV-s-NAP, a novel oncolytic measles virus strain armed with an H.pylori immunostimulatory bacterial transgene

Despite recent therapeutic advances, metastatic breast cancer (MBC) remains incurable. Engineered measles virus (MV) constructs based on the attenuated MV Edmonston vaccine platform have demonstrated significant oncolytic activity against solid tumors. The Helicobacter pylori neutrophil-activating p...

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Detalles Bibliográficos
Autores principales: Viker, Kimberly B., Steele, Michael B., Iankov, Ianko D., Concilio, Susanna C., Ammayappan, Arun, Bolon, Brad, Jenks, Nathan J., Goetz, Matthew P., Panagioti, Eleni, Federspiel, Mark J., Liu, Minetta C., Peng, Kah Whye, Galanis, Evanthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437807/
https://www.ncbi.nlm.nih.gov/pubmed/36092362
http://dx.doi.org/10.1016/j.omtm.2022.07.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437807/
https://www.ncbi.nlm.nih.gov/pubmed/36092362
http://dx.doi.org/10.1016/j.omtm.2022.07.014

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