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Hypoxia inhibits the cardiac I(K1) current through SUMO targeting Kir2.1 activation by PIP(2)
Cardiovascular diseases remain the leading cause of death worldwide. Most deaths are sudden and occur secondary to the occlusion of coronary arteries resulting in a rapid decrease in cellular oxygen levels. Acute hypoxia is proarrhythmic, leading to disordered electrical signals, conduction block, a...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437851/ https://www.ncbi.nlm.nih.gov/pubmed/36060074 http://dx.doi.org/10.1016/j.isci.2022.104969 |