miRSCAPE - inferring miRNA expression from scRNA-seq data

Our understanding of miRNA activity at cellular resolution is thwarted by the inability of standard scRNA-seq protocols to capture miRNAs. We introduce a novel tool, miRSCAPE, to infer miRNA expression in a sample from its RNA-seq profile. We establish miRSCAPE’s accuracy in 10 tumor and normal coho...

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Detalles Bibliográficos
Autores principales: Olgun, Gulden, Gopalan, Vishaka, Hannenhalli, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437856/
https://www.ncbi.nlm.nih.gov/pubmed/36060076
http://dx.doi.org/10.1016/j.isci.2022.104962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437856/
https://www.ncbi.nlm.nih.gov/pubmed/36060076
http://dx.doi.org/10.1016/j.isci.2022.104962

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