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miRSCAPE - inferring miRNA expression from scRNA-seq data
Our understanding of miRNA activity at cellular resolution is thwarted by the inability of standard scRNA-seq protocols to capture miRNAs. We introduce a novel tool, miRSCAPE, to infer miRNA expression in a sample from its RNA-seq profile. We establish miRSCAPE’s accuracy in 10 tumor and normal coho...
Autores principales: | Olgun, Gulden, Gopalan, Vishaka, Hannenhalli, Sridhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437856/ https://www.ncbi.nlm.nih.gov/pubmed/36060076 http://dx.doi.org/10.1016/j.isci.2022.104962 |
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