LDHA-mediated metabolic reprogramming promoted cardiomyocyte proliferation by alleviating ROS and inducing M2 macrophage polarization

AIMS: Metabolic switching during heart development contributes to postnatal cardiomyocyte (CM) cell cycle exit and loss of regenerative capacity in the mammalian heart. Metabolic control has potential for developing effective CM proliferation strategies. We sought to determine whether lactate dehydr...

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Detalles Bibliográficos
Autores principales: Chen, Yijin, Wu, Guangkai, Li, Mengsha, Hesse, Michael, Ma, Yusheng, Chen, Wei, Huang, Haoxiang, Liu, Yu, Xu, Wenlong, Tang, Yating, Zheng, Hao, Li, Chuling, Lin, Zhongqiu, Chen, Guojun, Liao, Wangjun, Liao, Yulin, Bin, Jianping, Chen, Yanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437906/
https://www.ncbi.nlm.nih.gov/pubmed/36057161
http://dx.doi.org/10.1016/j.redox.2022.102446

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