Oct4 cooperates with c-Myc to improve mesenchymal-to-endothelial transition and myocardial repair of cardiac-resident mesenchymal stem cells

BACKGROUND: Cardiac-resident mesenchymal stem cells (cMSCs) can exhibit fibrotic, proinflammatory, and proangiogenic phenotype in response to myocardial ischemia (Isch). How their phenotypic fate decisions are determined remains poorly understood. Here, we demonstrate that the cooperation of Oct4 an...

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Detalles Bibliográficos
Autores principales: Zhao, Lan, Wang, Jianshuo, Wang, Pengzhen, Deng, Zhanyu, Cui, Jin, Huang, Weiguang, Zhang, Shaoheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438134/
https://www.ncbi.nlm.nih.gov/pubmed/36056383
http://dx.doi.org/10.1186/s13287-022-03120-7

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