Inhibition of lncRNA NEAT1 induces dysfunction of fibroblast-like synoviocytes in rheumatoid arthritis via miRNA-338-3p-mediated regulation of glutamine metabolism

BACKGROUND: Rheumatoid arthritis (RA) is a systemic chronic autoimmune disease; cellular glutamine metabolism in fibroblast-like synoviocytes (FLSs) of RA was known to be essential for RA pathogenesis and progression. NEAT1, a long non-coding RNA, functions as an oncogene in diverse cancers. The exa...

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Detalles Bibliográficos
Autores principales: Zhang, Mei, Lu, Ning, Li, Hong-Jun, Guo, Xiao-Yun, Lu, Lu, Guo, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438172/
https://www.ncbi.nlm.nih.gov/pubmed/36050752
http://dx.doi.org/10.1186/s13018-022-03295-y

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