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Dynamic network model reveals distinct tau spreading patterns in early- and late-onset Alzheimer disease

BACKGROUND: The clinical features of Alzheimer’s disease (AD) vary substantially depending on whether the onset of cognitive deficits is early or late. The amount and distribution patterns of tau pathology are thought to play a key role in the clinical characteristics of AD, which spreads throughout...

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Detalles Bibliográficos
Autores principales: Lee, Wha Jin, Cho, Hanna, Baek, Min Seok, Kim, Han-Kyeol, Lee, Jae Hoon, Ryu, Young Hoon, Lyoo, Chul Hyoung, Seong, Joon-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438183/
https://www.ncbi.nlm.nih.gov/pubmed/36056405
http://dx.doi.org/10.1186/s13195-022-01061-0