Cargando…

Dynamic network model reveals distinct tau spreading patterns in early- and late-onset Alzheimer disease

BACKGROUND: The clinical features of Alzheimer’s disease (AD) vary substantially depending on whether the onset of cognitive deficits is early or late. The amount and distribution patterns of tau pathology are thought to play a key role in the clinical characteristics of AD, which spreads throughout...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Wha Jin, Cho, Hanna, Baek, Min Seok, Kim, Han-Kyeol, Lee, Jae Hoon, Ryu, Young Hoon, Lyoo, Chul Hyoung, Seong, Joon-Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438183/ https://www.ncbi.nlm.nih.gov/pubmed/36056405 http://dx.doi.org/10.1186/s13195-022-01061-0

Ejemplares similares

Principal components of tau positron emission tomography and longitudinal tau accumulation in Alzheimer’s disease
por: Cho, Hanna, et al.
Publicado: (2020)

Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer’s disease
por: Baek, Min Seok, et al.
Publicado: (2020)

Effect of A/T/N imaging biomarkers on impaired odor identification in Alzheimer's disease
por: Baek, Min Seok, et al.
Publicado: (2020)

Tau Positron Emission Tomography Imaging in Degenerative Parkinsonisms
por: Lyoo, Chul Hyoung, et al.
Publicado: (2018)

Annual Trends in the Incidence and Prevalence of Alzheimer's Disease in South Korea: A Nationwide Cohort Study
por: Baek, Min Seok, et al.
Publicado: (2022)

Temporal trajectory of biofluid markers in Parkinson’s disease
por: Baek, Min Seok, et al.
Publicado: (2021)

Distinct tau PET patterns in atrophy-defined subtypes of Alzheimer’s disease
por: Ossenkoppele, Rik, et al.
Publicado: (2020)

Asymmetric Parkinsonism With Progressive Nigrosomal Change Secondary to Kernohan’s Notch Phenomenon
por: Kim, Han-Kyeol, et al.
Publicado: (2022)

Association of Subcortical Structural Shapes With Tau, Amyloid, and Cortical Atrophy in Early-Onset and Late-Onset Alzheimer’s Disease
por: Lee, Eun-Chong, et al.
Publicado: (2020)

Effects of Alzheimer’s and Vascular Pathologies on Structural Connectivity in Early- and Late-Onset Alzheimer’s Disease
por: Lee, Wha Jin, et al.
Publicado: (2021)

Risks and Prognoses of Alzheimer's Disease and Vascular Dementia in Patients With Insomnia: A Nationwide Population-Based Study
por: Baek, Min Seok, et al.
Publicado: (2021)

Earlier Alzheimer’s disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading
por: Frontzkowski, Lukas, et al.
Publicado: (2022)

Ante‐ and postmortem tau in autosomal dominant and late‐onset Alzheimer’s disease
por: Chen, Charles D., et al.
Publicado: (2020)

A Patient with Recurrent Dyskinesia and Hyperpyrexia Syndrome
por: Baek, Min Seok, et al.
Publicado: (2017)

Assessment of Demographic, Genetic, and Imaging Variables Associated With Brain Resilience and Cognitive Resilience to Pathological Tau in Patients With Alzheimer Disease
por: Ossenkoppele, Rik, et al.
Publicado: (2020)

Genetic factors affecting dopaminergic deterioration during the premotor stage of Parkinson disease
por: Lee, Myung Jun, et al.
Publicado: (2021)

Author Correction: Genetic factors affecting dopaminergic deterioration during the premotor stage of Parkinson disease
por: Lee, Myung Jun, et al.
Publicado: (2022)

Clinical Features Indicating Nigrostriatal Dopaminergic Degeneration in Drug-Induced Parkinsonism
por: Lee, Seung Ha, et al.
Publicado: (2017)

A Computed Tomography-Based Spatial Normalization for the Analysis of [(18)F] Fluorodeoxyglucose Positron Emission Tomography of the Brain
por: Cho, Hanna, et al.
Publicado: (2014)

Feasibility of Computed Tomography-Guided Methods for Spatial Normalization of Dopamine Transporter Positron Emission Tomography Image
por: Kim, Jin Su, et al.
Publicado: (2015)

Distinct Patterns of Interhemispheric Connectivity in Patients With Early- and Late-Onset Alzheimer’s Disease
por: Li, Kai-Cheng, et al.
Publicado: (2018)

Evaluation of Utilizing the Distinct Genes as Predictive Biomarkers in Late-Onset Alzheimer's Disease
por: Kenanoglu, Sercan, et al.
Publicado: (2022)

Regional Comparison of Imaging Biomarkers in the Striatum between Early- and Late-onset Alzheimer’s Disease
por: Kim, Ji Eun, et al.
Publicado: (2022)

Extracellular vesicles drive tau spreading in Alzheimer's disease
por: Ruan, Zhi
Publicado: (2021)

Possible Mechanisms of Tau Spread and Toxicity in Alzheimer’s Disease
por: Zhang, Huiqin, et al.
Publicado: (2021)

Assessing the applicability of PMOD residence times model for PET image-based radiation dosimetry
por: Oh, Se Jong, et al.
Publicado: (2023)

Late-onset vs nonmendelian early-onset Alzheimer disease: A distinction without a difference?
por: Reitz, Christiane, et al.
Publicado: (2020)

Association between physical activity and conversion from mild cognitive impairment to dementia
por: Kim, Yeo Jin, et al.
Publicado: (2020)

Tau and TDP-43 synergy: a novel therapeutic target for sporadic late-onset Alzheimer’s disease
por: Latimer, Caitlin S., et al.
Publicado: (2021)

FMRI Complexity Correlates with Tau-PET and Cognitive Decline in Late-Onset and Autosomal Dominant Alzheimer’s Disease
por: Jann, Kay, et al.
Publicado: (2023)

Presynaptic Dopaminergic Dysfunction Was Overestimated in Huntington’s Disease Presenting as Young Age-Onset Parkinsonism
por: Kim, Taewon, et al.
Publicado: (2022)

Distinct cerebral small vessel disease impairment in early‐ and late‐onset Alzheimer's disease
por: Luo, Xiao, et al.
Publicado: (2023)

Clinical Characteristics of Early-Onset and Late-Onset Leigh Syndrome
por: Hong, Chan-Mi, et al.
Publicado: (2020)

Differential associations between neocortical tau pathology and blood flow with cognitive deficits in early-onset vs late-onset Alzheimer’s disease
por: Visser, Denise, et al.
Publicado: (2022)

Distinct fiber-specific white matter reductions pattern in early- and late-onset Alzheimer’s disease
por: Luo, Xiao, et al.
Publicado: (2021)

A Dextral Primary Progressive Aphasia Patient with Right Dominant Hypometabolism and Tau Accumulation and Left Dominant Amyloid Accumulation
por: Jang, Young Kyoung, et al.
Publicado: (2016)

Estrogen Receptor Status Predicts Late-Onset Skeletal Recurrence in Breast Cancer Patients
por: Han, Hyun Ho, et al.
Publicado: (2016)

Identification of the Sites of Tau Hyperphosphorylation and Activation of Tau Kinases in Synucleinopathies and Alzheimer’s Diseases
por: Duka, Valeriy, et al.
Publicado: (2013)

The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer’s disease
por: Hopp, Sarah C., et al.
Publicado: (2018)

Mechanisms of Pathogenic Tau and Aβ Protein Spreading in Alzheimer’s Disease
por: d‘Errico, Paolo, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ep72b8bvr5p6a1vji2utmg8kfp