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LRP1 is a neuronal receptor for α-synuclein uptake and spread

BACKGROUND: The aggregation and spread of α-synuclein (α-Syn) protein and related neuronal toxicity are the key pathological features of Parkinson’s disease (PD) and Lewy body dementia (LBD). Studies have shown that pathological species of α-Syn and tau can spread in a prion-like manner between neur...

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Detalles Bibliográficos
Autores principales:	Chen, Kai, Martens, Yuka A., Meneses, Axel, Ryu, Daniel H., Lu, Wenyan, Raulin, Ana Caroline, Li, Fuyao, Zhao, Jing, Chen, Yixing, Jin, Yunjung, Linares, Cynthia, Goodwin, Marshall, Li, Yonghe, Liu, Chia-Chen, Kanekiyo, Takahisa, Holtzman, David M., Golde, Todd E., Bu, Guojun, Zhao, Na
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438229/ https://www.ncbi.nlm.nih.gov/pubmed/36056345 http://dx.doi.org/10.1186/s13024-022-00560-w

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