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Multiethnic polygenic risk prediction in diverse populations through transfer learning

Polygenic risk scores (PRS) leverage the genetic contribution of an individual’s genotype to a complex trait by estimating disease risk. Traditional PRS prediction methods are predominantly for the European population. The accuracy of PRS prediction in non-European populations is diminished due to m...

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Detalles Bibliográficos
Autores principales:	Tian, Peixin, Chan, Tsai Hor, Wang, Yong-Fei, Yang, Wanling, Yin, Guosheng, Zhang, Yan Dora
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438789/ https://www.ncbi.nlm.nih.gov/pubmed/36061179 http://dx.doi.org/10.3389/fgene.2022.906965

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