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Bioactive natural products in COVID-19 therapy

The devastating COVID-19 pandemic has caused more than six million deaths worldwide during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic bullets still do not exist. Numerous natural products (cordycepin, gallinamide A, plitidepsin, telocinobufagin, and tyloph...

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Detalles Bibliográficos
Autores principales: Wang, Zhonglei, Wang, Ning, Yang, Liyan, Song, Xian-qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438897/
https://www.ncbi.nlm.nih.gov/pubmed/36059994
http://dx.doi.org/10.3389/fphar.2022.926507
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author Wang, Zhonglei
Wang, Ning
Yang, Liyan
Song, Xian-qing
author_facet Wang, Zhonglei
Wang, Ning
Yang, Liyan
Song, Xian-qing
author_sort Wang, Zhonglei
collection PubMed
description The devastating COVID-19 pandemic has caused more than six million deaths worldwide during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic bullets still do not exist. Numerous natural products (cordycepin, gallinamide A, plitidepsin, telocinobufagin, and tylophorine) have been widely studied and play a potential function in treating COVID-19. In this paper, we reviewed published studies (from May 2021 to April 2022) relating closely to bioactive natural products (isolated from medicinal plants, animals products, and marine organisms) in COVID-19 therapy in vitro to provide some essential guidance for anti-SARS-CoV-2 drug research and development.
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spelling pubmed-94388972022-09-03 Bioactive natural products in COVID-19 therapy Wang, Zhonglei Wang, Ning Yang, Liyan Song, Xian-qing Front Pharmacol Pharmacology The devastating COVID-19 pandemic has caused more than six million deaths worldwide during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic bullets still do not exist. Numerous natural products (cordycepin, gallinamide A, plitidepsin, telocinobufagin, and tylophorine) have been widely studied and play a potential function in treating COVID-19. In this paper, we reviewed published studies (from May 2021 to April 2022) relating closely to bioactive natural products (isolated from medicinal plants, animals products, and marine organisms) in COVID-19 therapy in vitro to provide some essential guidance for anti-SARS-CoV-2 drug research and development. Frontiers Media S.A. 2022-08-19 /pmc/articles/PMC9438897/ /pubmed/36059994 http://dx.doi.org/10.3389/fphar.2022.926507 Text en Copyright © 2022 Wang, Wang, Yang and Song. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Wang, Zhonglei
Wang, Ning
Yang, Liyan
Song, Xian-qing
Bioactive natural products in COVID-19 therapy
title Bioactive natural products in COVID-19 therapy
title_full Bioactive natural products in COVID-19 therapy
title_fullStr Bioactive natural products in COVID-19 therapy
title_full_unstemmed Bioactive natural products in COVID-19 therapy
title_short Bioactive natural products in COVID-19 therapy
title_sort bioactive natural products in covid-19 therapy
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438897/
https://www.ncbi.nlm.nih.gov/pubmed/36059994
http://dx.doi.org/10.3389/fphar.2022.926507
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