Kill two birds with one stone: Engineered exosome-mediated delivery of cholesterol modified YY1-siRNA enhances chemoradiotherapy sensitivity of glioblastoma

Glioblastoma (GBM) is the most malignant tumor of the central nervous system in adults. Irradiation (IR) and temozolomide (TMZ) play an extremely important role in the treatment of GBM. However, major impediments to effective treatment are postoperative tumor recurrence and acquired resistance to ch...

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Detalles Bibliográficos
Autores principales: Liu, Xiao, Cao, Zhengcong, Liu, Nannan, Gao, Guangxun, Du, Mingrui, Wang, Yingwen, Cheng, Boyang, Zhu, Maorong, Jia, Bo, Pan, Luxiang, Zhang, Wangqian, Jiang, Yuran, He, Wei, Xu, Linlin, Zhang, Wei, An, Qunxing, Guo, Qingdong, Gu, Jintao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438942/
https://www.ncbi.nlm.nih.gov/pubmed/36059990
http://dx.doi.org/10.3389/fphar.2022.975291

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