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Single-cell analysis of gene expression in the substantia nigra pars compacta of a pesticide-induced mouse model of Parkinson’s disease

Exposure to pesticides in humans increases the risk of Parkinson’s disease (PD), but the mechanisms remain poorly understood. To elucidate these pathways, we dosed C57BL/6J mice with a combination of the pesticides maneb and paraquat. Behavioral analysis revealed motor deficits consistent with PD. S...

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Detalles Bibliográficos
Autores principales:	Khan, Arshad H., Lee, Lydia K., Smith, Desmond J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438968/ https://www.ncbi.nlm.nih.gov/pubmed/36117858 http://dx.doi.org/10.1515/tnsci-2022-0237

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