Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation

Acyl-CoA synthetase 1 (ACSL1) is an enzyme that converts fatty acids to acyl-CoA-derivatives for lipid catabolism and lipid synthesis in general and can provide substrates for the production of mediators of inflammation in monocytes and macrophages. Acsl1 expression is increased by hyperglycemia and...

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Detalles Bibliográficos
Autores principales: Thevkar-Nagesh, Prashanth, Habault, Justine, Voisin, Maud, Ruff, Sophie E., Ha, Susan, Ruoff, Rachel, Chen, Xi, Rawal, Shruti, Zahr, Tarik, Szabo, Gyongyi, Rogatsky, Inez, Fisher, Edward A., Garabedian, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439225/
https://www.ncbi.nlm.nih.gov/pubmed/36054206
http://dx.doi.org/10.1371/journal.pone.0272986

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