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Should the COVID-19 lockdown be relaxed or intensified in case a vaccine becomes available?
Immediately after the start of the COVID-19 pandemic in Early 2020, most affected countries reacted with strict lockdown to limit the spread of the virus. Since that time, the measures were adapted on a short time basis according to certain numbers (i.e., number of infected, utilization of intensive...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439227/ https://www.ncbi.nlm.nih.gov/pubmed/36054113 http://dx.doi.org/10.1371/journal.pone.0273557 |
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author | Buratto, Alessandra Muttoni, Maddalena Wrzaczek, Stefan Freiberger, Michael |
author_facet | Buratto, Alessandra Muttoni, Maddalena Wrzaczek, Stefan Freiberger, Michael |
author_sort | Buratto, Alessandra |
collection | PubMed |
description | Immediately after the start of the COVID-19 pandemic in Early 2020, most affected countries reacted with strict lockdown to limit the spread of the virus. Since that time, the measures were adapted on a short time basis according to certain numbers (i.e., number of infected, utilization of intensive care units). Implementing a long-term optimal strategy was not possible since a forecast when R&D will succeed in developing an effective vaccination was not available. Our paper closes this gap by assuming a stochastic arrival rate of the COVID-19 vaccine with the corresponding change in the optimal policy regarding the accompanying optimal lockdown measures. The first finding is that the lockdown should be intensified after the vaccine approval if the pace of the vaccination campaign is rather slow. Secondly, the anticipation of the vaccination arrival also leads to a stricter lockdown in the period without vaccination. For both findings, an intuitive explanation is offered. |
format | Online Article Text |
id | pubmed-9439227 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-94392272022-09-03 Should the COVID-19 lockdown be relaxed or intensified in case a vaccine becomes available? Buratto, Alessandra Muttoni, Maddalena Wrzaczek, Stefan Freiberger, Michael PLoS One Research Article Immediately after the start of the COVID-19 pandemic in Early 2020, most affected countries reacted with strict lockdown to limit the spread of the virus. Since that time, the measures were adapted on a short time basis according to certain numbers (i.e., number of infected, utilization of intensive care units). Implementing a long-term optimal strategy was not possible since a forecast when R&D will succeed in developing an effective vaccination was not available. Our paper closes this gap by assuming a stochastic arrival rate of the COVID-19 vaccine with the corresponding change in the optimal policy regarding the accompanying optimal lockdown measures. The first finding is that the lockdown should be intensified after the vaccine approval if the pace of the vaccination campaign is rather slow. Secondly, the anticipation of the vaccination arrival also leads to a stricter lockdown in the period without vaccination. For both findings, an intuitive explanation is offered. Public Library of Science 2022-09-02 /pmc/articles/PMC9439227/ /pubmed/36054113 http://dx.doi.org/10.1371/journal.pone.0273557 Text en © 2022 Buratto et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Buratto, Alessandra Muttoni, Maddalena Wrzaczek, Stefan Freiberger, Michael Should the COVID-19 lockdown be relaxed or intensified in case a vaccine becomes available? |
title | Should the COVID-19 lockdown be relaxed or intensified in case a vaccine becomes available? |
title_full | Should the COVID-19 lockdown be relaxed or intensified in case a vaccine becomes available? |
title_fullStr | Should the COVID-19 lockdown be relaxed or intensified in case a vaccine becomes available? |
title_full_unstemmed | Should the COVID-19 lockdown be relaxed or intensified in case a vaccine becomes available? |
title_short | Should the COVID-19 lockdown be relaxed or intensified in case a vaccine becomes available? |
title_sort | should the covid-19 lockdown be relaxed or intensified in case a vaccine becomes available? |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439227/ https://www.ncbi.nlm.nih.gov/pubmed/36054113 http://dx.doi.org/10.1371/journal.pone.0273557 |
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