Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses

Influenza A viruses pose a significant threat globally each year, underscoring the need for a vaccine- or antiviral-based broad-protection strategy. Here, we describe a chimeric monoclonal antibody, C12H5, that offers neutralization against seasonal and pandemic H1N1 viruses, and cross-protection ag...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Chen, Junyu, Zheng, Qingbing, Xue, Wenhui, Zhang, Limin, Rong, Rui, Zhang, Sibo, Wang, Qian, Hong, Minqing, Zhang, Yuyun, Cui, Lingyan, He, Maozhou, Lu, Zhen, Zhang, Zhenyong, Chi, Xin, Li, Jinjin, Huang, Yang, Wang, Hong, Tang, Jixian, Ying, Dong, Zhou, Lizhi, Wang, Yingbin, Yu, Hai, Zhang, Jun, Gu, Ying, Chen, Yixin, Li, Shaowei, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439264/
https://www.ncbi.nlm.nih.gov/pubmed/36056024
http://dx.doi.org/10.1038/s41467-022-32926-5

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