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Spike-based adenovirus vectored COVID-19 vaccine does not aggravate heart damage after ischemic injury in mice

An unprecedented number of COVID-19 vaccination campaign are under way worldwide. The spike protein of SARS-CoV-2, which majorly binds to the host receptor angiotensin converting enzyme 2 (ACE2) for cell entry, is used by most of the vaccine as antigen. ACE2 is highly expressed in the heart and has...

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Detalles Bibliográficos
Autores principales: Gu, Shanshan, Chen, Zhongyan, Meng, Xiangfu, Liu, Ge, Xu, He, Huang, Liying, Wu, Linwei, Gong, Jixing, Chen, Ding, Xue, Bingqing, Zhu, Lihang, Wan, Zhongjun, Lin, Jianqing, Cai, Xiaolong, Zhang, Xiaoyan, Wang, Jia, Zhang, Donghui, Cao, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439278/
https://www.ncbi.nlm.nih.gov/pubmed/36056135
http://dx.doi.org/10.1038/s42003-022-03875-y

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