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Ligand‐Enabled β‐C(sp(3))−H Lactamization of Tosyl‐Protected Aliphatic Amides Using a Practical Oxidant

The development of C(sp(3))−H functionalization reactions that use common protecting groups and practical oxidants remains a significant challenge. Herein we report a monoprotected aminoethyl thioether (MPAThio) ligand‐enabled β‐C(sp(3))−H lactamization of tosyl‐protected aliphatic amides using tert...

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Detalles Bibliográficos
Autores principales: Zhuang, Zhe, Liu, Shuang, Cheng, Jin‐Tang, Yeung, Kap‐Sun, Qiao, Jennifer X., Meanwell, Nicholas A., Yu, Jin‐Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439703/
https://www.ncbi.nlm.nih.gov/pubmed/35790471
http://dx.doi.org/10.1002/anie.202207354

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