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Variability of pulmonary nodule volumetry on coronary CT angiograms

This study aims to investigate the variability of pulmonary nodule (PN) volumetry on multiphase coronary CT angiograms (CCTA). Two radiologists reviewed 5973 CCTA scans in this cross-sectional study to detect incidental solid noncalcified PNs measuring between 5 and 8 mm. Each radiologist measured t...

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Autores principales: Pinto, Erique, Penha, Diana, Hochhegger, Bruno, Monaghan, Colin, Marchiori, Edson, Taborda-Barata, Luís, Irion, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439735/
https://www.ncbi.nlm.nih.gov/pubmed/36107569
http://dx.doi.org/10.1097/MD.0000000000030332
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author Pinto, Erique
Penha, Diana
Hochhegger, Bruno
Monaghan, Colin
Marchiori, Edson
Taborda-Barata, Luís
Irion, Klaus
author_facet Pinto, Erique
Penha, Diana
Hochhegger, Bruno
Monaghan, Colin
Marchiori, Edson
Taborda-Barata, Luís
Irion, Klaus
author_sort Pinto, Erique
collection PubMed
description This study aims to investigate the variability of pulmonary nodule (PN) volumetry on multiphase coronary CT angiograms (CCTA). Two radiologists reviewed 5973 CCTA scans in this cross-sectional study to detect incidental solid noncalcified PNs measuring between 5 and 8 mm. Each radiologist measured the nodules’ diameters and volume, in systole and diastole, using 2 commercially available software packages to analyze PNs. Bland-Altman analysis was applied between different observers, software packages, and cardiac phases. Bland-Altman subanalysis for the systolic and diastolic datasets were also performed. A total of 195 PNs were detected within the inclusion criteria and measured in systole and diastole. Bland-Altman analysis was used to test the variability of volumetry between cardiac phases ([−47.0%; 52.3%]), software packages ([−50.2%; 68.2%]), and observers ([−14.5%; 27.8%]). The inter-observer variability of the systolic and diastolic subsets was [−13.6%; 31.4%] and [−13.9%; 19.7%], respectively. Using diastolic volume measurements, the variability of PN volumetry on CCTA scans is similar to the reported variability of volumetry on low-dose CT scans. Therefore, growth estimation of PNs on CCTA scans could be feasible.
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spelling pubmed-94397352022-09-06 Variability of pulmonary nodule volumetry on coronary CT angiograms Pinto, Erique Penha, Diana Hochhegger, Bruno Monaghan, Colin Marchiori, Edson Taborda-Barata, Luís Irion, Klaus Medicine (Baltimore) Research Article This study aims to investigate the variability of pulmonary nodule (PN) volumetry on multiphase coronary CT angiograms (CCTA). Two radiologists reviewed 5973 CCTA scans in this cross-sectional study to detect incidental solid noncalcified PNs measuring between 5 and 8 mm. Each radiologist measured the nodules’ diameters and volume, in systole and diastole, using 2 commercially available software packages to analyze PNs. Bland-Altman analysis was applied between different observers, software packages, and cardiac phases. Bland-Altman subanalysis for the systolic and diastolic datasets were also performed. A total of 195 PNs were detected within the inclusion criteria and measured in systole and diastole. Bland-Altman analysis was used to test the variability of volumetry between cardiac phases ([−47.0%; 52.3%]), software packages ([−50.2%; 68.2%]), and observers ([−14.5%; 27.8%]). The inter-observer variability of the systolic and diastolic subsets was [−13.6%; 31.4%] and [−13.9%; 19.7%], respectively. Using diastolic volume measurements, the variability of PN volumetry on CCTA scans is similar to the reported variability of volumetry on low-dose CT scans. Therefore, growth estimation of PNs on CCTA scans could be feasible. Lippincott Williams & Wilkins 2022-09-02 /pmc/articles/PMC9439735/ /pubmed/36107569 http://dx.doi.org/10.1097/MD.0000000000030332 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Pinto, Erique
Penha, Diana
Hochhegger, Bruno
Monaghan, Colin
Marchiori, Edson
Taborda-Barata, Luís
Irion, Klaus
Variability of pulmonary nodule volumetry on coronary CT angiograms
title Variability of pulmonary nodule volumetry on coronary CT angiograms
title_full Variability of pulmonary nodule volumetry on coronary CT angiograms
title_fullStr Variability of pulmonary nodule volumetry on coronary CT angiograms
title_full_unstemmed Variability of pulmonary nodule volumetry on coronary CT angiograms
title_short Variability of pulmonary nodule volumetry on coronary CT angiograms
title_sort variability of pulmonary nodule volumetry on coronary ct angiograms
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439735/
https://www.ncbi.nlm.nih.gov/pubmed/36107569
http://dx.doi.org/10.1097/MD.0000000000030332
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