A Small Blemish: Isotretinoin-Induced Microscopic Colitis

Microscopic colitis is a form of colonic inflammation that presents with chronic nonbloody diarrhea that can only be diagnosed histologically with biopsies obtained during colonoscopy. We report a rare case of isotretinoin-induced microscopic colitis in a patient who was prescribed this medication f...

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Autores principales: Dukate, Loren R., Pak, Kevin, O'Connell, William, Junga, Zachary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439757/
https://www.ncbi.nlm.nih.gov/pubmed/36072354
http://dx.doi.org/10.14309/crj.0000000000000838
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author Dukate, Loren R.
Pak, Kevin
O'Connell, William
Junga, Zachary
author_facet Dukate, Loren R.
Pak, Kevin
O'Connell, William
Junga, Zachary
author_sort Dukate, Loren R.
collection PubMed
description Microscopic colitis is a form of colonic inflammation that presents with chronic nonbloody diarrhea that can only be diagnosed histologically with biopsies obtained during colonoscopy. We report a rare case of isotretinoin-induced microscopic colitis in a patient who was prescribed this medication for nodular acne with a 1-year history of nonbloody diarrhea, bloating, cramping, and foul-smelling gas. Cessation of this medication in addition to initiating treatment with budesonide resulted in remission of the patient's symptoms. The presence of chronic diarrhea in patients who are taking isotretinoin should raise suspicion for this condition and warrant further investigation.
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spelling pubmed-94397572022-09-06 A Small Blemish: Isotretinoin-Induced Microscopic Colitis Dukate, Loren R. Pak, Kevin O'Connell, William Junga, Zachary ACG Case Rep J Case Report Microscopic colitis is a form of colonic inflammation that presents with chronic nonbloody diarrhea that can only be diagnosed histologically with biopsies obtained during colonoscopy. We report a rare case of isotretinoin-induced microscopic colitis in a patient who was prescribed this medication for nodular acne with a 1-year history of nonbloody diarrhea, bloating, cramping, and foul-smelling gas. Cessation of this medication in addition to initiating treatment with budesonide resulted in remission of the patient's symptoms. The presence of chronic diarrhea in patients who are taking isotretinoin should raise suspicion for this condition and warrant further investigation. Wolters Kluwer 2022-09-01 /pmc/articles/PMC9439757/ /pubmed/36072354 http://dx.doi.org/10.14309/crj.0000000000000838 Text en Written work prepared by employees of the Federal Government as part of their official duties is, under the U.S. Copyright Act, a “work of the United States Government” for which copyright protection under Title 17 of the United States Code is not available. As such, copyright does not extend to the contributions of employees of the Federal Government. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Dukate, Loren R.
Pak, Kevin
O'Connell, William
Junga, Zachary
A Small Blemish: Isotretinoin-Induced Microscopic Colitis
title A Small Blemish: Isotretinoin-Induced Microscopic Colitis
title_full A Small Blemish: Isotretinoin-Induced Microscopic Colitis
title_fullStr A Small Blemish: Isotretinoin-Induced Microscopic Colitis
title_full_unstemmed A Small Blemish: Isotretinoin-Induced Microscopic Colitis
title_short A Small Blemish: Isotretinoin-Induced Microscopic Colitis
title_sort small blemish: isotretinoin-induced microscopic colitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439757/
https://www.ncbi.nlm.nih.gov/pubmed/36072354
http://dx.doi.org/10.14309/crj.0000000000000838
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