The Anti-Proliferative Lichen-Compound Protolichesterinic Acid Inhibits Oxidative Phosphorylation and Is Processed via the Mercapturic Pathway in Cancer Cells

The lichen compound protolichesterinic acid (PA) has an anti-proliferative effect against several cancer cell lines of different origin. This effect cannot be explained by the known inhibitory activity of PA against 5- and 12-lipoxygenases. The aim was therefore to search for mechanisms for the anti...

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Detalles Bibliográficos
Autores principales: Jóhannsson, Freyr, Cherek, Paulina, Xu, Maonian, Rolfsson, Óttar, Ögmundsdóttir, Helga M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439851/
https://www.ncbi.nlm.nih.gov/pubmed/34521132
http://dx.doi.org/10.1055/a-1579-6454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439851/
https://www.ncbi.nlm.nih.gov/pubmed/34521132
http://dx.doi.org/10.1055/a-1579-6454

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