Lack of adducin impairs the stability of endothelial adherens and tight junctions and may be required for cAMP-Rac1-mediated endothelial barrier stabilization

Adducin (Add) is an actin binding protein participating in the stabilization of actin/spectrin networks, epithelial junctional turnover and cardiovascular disorders such as hypertension. Recently, we demonstrated that Add is required for adherens junctions (AJ) integrity. Here we hypothesized that A...

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Detalles Bibliográficos
Autores principales: Moztarzadeh, Sina, Radeva, Mariya Y., Sepic, Sara, Schuster, Katharina, Hamad, Ibrahim, Waschke, Jens, García-Ponce, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440001/
https://www.ncbi.nlm.nih.gov/pubmed/36056066
http://dx.doi.org/10.1038/s41598-022-18964-5

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