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Transplantation of PSC-derived myogenic progenitors counteracts disease phenotypes in FSHD mice

Facioscapulohumeral muscular dystrophy (FSHD) is a genetically dominant progressive myopathy caused by improper silencing of the DUX4 gene, leading to fibrosis, muscle atrophy, and fatty replacement. Approaches focused on muscle regeneration through the delivery of stem cells represent an attractive...

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Detalles Bibliográficos
Autores principales:	Azzag, Karim, Bosnakovski, Darko, Tungtur, Sudheer, Salama, Peter, Kyba, Michael, Perlingeiro, Rita C. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440030/ https://www.ncbi.nlm.nih.gov/pubmed/36056021 http://dx.doi.org/10.1038/s41536-022-00249-0

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