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A novel scaled-gamma-tanh (SGT) activation function in 3D CNN applied for MRI classification

Activation functions in the neural network are responsible for ‘firing’ the nodes in it. In a deep neural network they ‘activate’ the features to reduce feature redundancy and learn the complex pattern by adding non-linearity in the network to learn task-specific goals. In this paper, we propose a s...

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Autores principales: Khagi, Bijen, Kwon, Goo-Rak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440075/
https://www.ncbi.nlm.nih.gov/pubmed/36056069
http://dx.doi.org/10.1038/s41598-022-19020-y
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author Khagi, Bijen
Kwon, Goo-Rak
author_facet Khagi, Bijen
Kwon, Goo-Rak
author_sort Khagi, Bijen
collection PubMed
description Activation functions in the neural network are responsible for ‘firing’ the nodes in it. In a deep neural network they ‘activate’ the features to reduce feature redundancy and learn the complex pattern by adding non-linearity in the network to learn task-specific goals. In this paper, we propose a simple and interesting activation function based on the combination of scaled gamma correction and hyperbolic tangent function, which we call Scaled Gamma Tanh (SGT) activation. The proposed activation function is applied in two steps, first is the calculation of gamma version as y = f(x) = ax(α) for x < 0 and y = f(x) = bx(β) for x ≥ 0, second is obtaining the squashed value as z = tanh(y). The variables a and b are user-defined constant values whereas [Formula: see text] and [Formula: see text] are channel-based learnable parameters. We analyzed the behavior of the proposed SGT activation function against other popular activation functions like ReLU, Leaky-ReLU, and tanh along with their role to confront vanishing/exploding gradient problems. For this, we implemented the SGT activation functions in a 3D Convolutional neural network (CNN) for the classification of magnetic resonance imaging (MRIs). More importantly to support our proposed idea we have presented a thorough analysis via histogram of inputs and outputs in activation layers along with weights/bias plot and t-SNE (t-Distributed Stochastic Neighbor Embedding) projection of fully connected layer for the trained CNN models. Our results in MRI classification show SGT outperforms standard ReLU and tanh activation in all cases i.e., final validation accuracy, final validation loss, test accuracy, Cohen’s kappa score, and Precision.
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spelling pubmed-94400752022-09-04 A novel scaled-gamma-tanh (SGT) activation function in 3D CNN applied for MRI classification Khagi, Bijen Kwon, Goo-Rak Sci Rep Article Activation functions in the neural network are responsible for ‘firing’ the nodes in it. In a deep neural network they ‘activate’ the features to reduce feature redundancy and learn the complex pattern by adding non-linearity in the network to learn task-specific goals. In this paper, we propose a simple and interesting activation function based on the combination of scaled gamma correction and hyperbolic tangent function, which we call Scaled Gamma Tanh (SGT) activation. The proposed activation function is applied in two steps, first is the calculation of gamma version as y = f(x) = ax(α) for x < 0 and y = f(x) = bx(β) for x ≥ 0, second is obtaining the squashed value as z = tanh(y). The variables a and b are user-defined constant values whereas [Formula: see text] and [Formula: see text] are channel-based learnable parameters. We analyzed the behavior of the proposed SGT activation function against other popular activation functions like ReLU, Leaky-ReLU, and tanh along with their role to confront vanishing/exploding gradient problems. For this, we implemented the SGT activation functions in a 3D Convolutional neural network (CNN) for the classification of magnetic resonance imaging (MRIs). More importantly to support our proposed idea we have presented a thorough analysis via histogram of inputs and outputs in activation layers along with weights/bias plot and t-SNE (t-Distributed Stochastic Neighbor Embedding) projection of fully connected layer for the trained CNN models. Our results in MRI classification show SGT outperforms standard ReLU and tanh activation in all cases i.e., final validation accuracy, final validation loss, test accuracy, Cohen’s kappa score, and Precision. Nature Publishing Group UK 2022-09-02 /pmc/articles/PMC9440075/ /pubmed/36056069 http://dx.doi.org/10.1038/s41598-022-19020-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Khagi, Bijen
Kwon, Goo-Rak
A novel scaled-gamma-tanh (SGT) activation function in 3D CNN applied for MRI classification
title A novel scaled-gamma-tanh (SGT) activation function in 3D CNN applied for MRI classification
title_full A novel scaled-gamma-tanh (SGT) activation function in 3D CNN applied for MRI classification
title_fullStr A novel scaled-gamma-tanh (SGT) activation function in 3D CNN applied for MRI classification
title_full_unstemmed A novel scaled-gamma-tanh (SGT) activation function in 3D CNN applied for MRI classification
title_short A novel scaled-gamma-tanh (SGT) activation function in 3D CNN applied for MRI classification
title_sort novel scaled-gamma-tanh (sgt) activation function in 3d cnn applied for mri classification
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440075/
https://www.ncbi.nlm.nih.gov/pubmed/36056069
http://dx.doi.org/10.1038/s41598-022-19020-y
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