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Phospholipase D2 controls bone homeostasis by modulating M-CSF-dependent osteoclastic cell migration and microtubule stability

Phospholipase D2 (PLD2), a signaling protein, plays a central role in cellular communication and various biological processes. Here, we show that PLD2 contributes to bone homeostasis by regulating bone resorption through osteoclastic cell migration and microtubule-dependent cytoskeletal organization...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Ju, Lee, Dong-Kyo, Jin, Xian, Che, Xiangguo, Ryu, Sung Ho, Choi, Je-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440116/
https://www.ncbi.nlm.nih.gov/pubmed/35945449
http://dx.doi.org/10.1038/s12276-022-00820-1