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A TGFβR inhibitor represses keratin-7 expression in 3D cultures of human salivary gland progenitor cells
Salivary gland tissue engineering offers an attractive alternative for the treatment of radiation-induced xerostomia. Key to the success of this approach is the maintenance and expansion of secretory acinar cells in vitro. However, recent studies revealed that in vitro culture of primary salivary gl...
Autores principales: | Fowler, Eric W., van Venrooy, Emmett J., Witt, Robert L., Jia, Xinqiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440137/ https://www.ncbi.nlm.nih.gov/pubmed/36056161 http://dx.doi.org/10.1038/s41598-022-19253-x |
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