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Rise of the human-mouse chimeric brain models

Human-mouse chimeras offer advantages for studying the pathophysiology of human cells in vivo. Chimeric mouse brains have been created by engrafting human fetal tissue- or pluripotent stem cell-derived progenitor cells into the neonatal mouse brain. This provides new opportunities to understand huma...

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Detalles Bibliográficos
Autores principales: Jiang, Peng, Alam, Mahabub Maraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440171/
https://www.ncbi.nlm.nih.gov/pubmed/36056167
http://dx.doi.org/10.1186/s13619-022-00135-6