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KLHL3 deficiency in mice ameliorates obesity, insulin resistance, and nonalcoholic fatty liver disease by regulating energy expenditure

Obesity is a growing global epidemic that can cause serious adverse health consequences, including insulin resistance (IR) and nonalcoholic fatty liver disease (NAFLD). Obesity development can be attributed to energy imbalance and metabolic inflexibility. Here, we demonstrated that lack of Kelch-lik...

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Detalles Bibliográficos
Autores principales: Jang, Ju-hong, Lee, Jeong Woong, Cho, Min Ji, Hwang, Byungtae, Kwon, Min-Gi, Kim, Dong-Hwan, Lee, Nam-Kyung, Lee, Jangwook, Park, Young-Jun, Yang, Yong Ryoul, Kim, Jinchul, Kim, Yong-Hoon, An, Tae Hyeon, Oh, Kyoung-Jin, Bae, Kwang-Hee, Park, Jong-Gil, Min, Jeong-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440235/
https://www.ncbi.nlm.nih.gov/pubmed/36028759
http://dx.doi.org/10.1038/s12276-022-00833-w